4HKJ

Structure of Cowpox CPXV203 in complex with MHCI (H-2Kb)

Summary for 4HKJ

Entry DOI	10.2210/pdb4hkj/pdb
Descriptor	H-2 class I histocompatibility antigen, K-B alpha chain, Beta-2-microglobulin, Ovalbumin, ... (5 entities in total)
Functional Keywords	viral immune evasion proteins, antigen presentation, structural genomics, niaid, national institute of allergy and infectious diseases, center for structural genomics of infectious diseases, csgid, inhibitor, intracellular, immune system-viral protein complex, immune system/viral protein
Biological source	Mus musculus (mouse) More
Cellular location	Membrane; Single-pass type I membrane protein: P01901 Secreted . Note=(Microbial infection) In the presence of M: P61769 Secreted : P01012
Total number of polymer chains	16
Total formula weight	275987.25
Authors	McCoy IV, W.H.,Fremont, D.H.,Center for Structural Genomics of Infectious Diseases (CSGID) (deposition date: 2012-10-15, release date: 2012-11-14, Last modification date: 2023-12-06)
Primary citation	McCoy, W.H.,Wang, X.,Yokoyama, W.M.,Hansen, T.H.,Fremont, D.H. Structural Mechanism of ER Retrieval of MHC Class I by Cowpox. Plos Biol., 10:e1001432-e1001432, 2012 Cited by PubMed: 23209377 DOI: 10.1371/journal.pbio.1001432 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3 Å)

Structure validation