4HAF

Crystal structure of fc-fragment of human IgG2 antibody (primitive crystal form)

Summary for 4HAF

Entry DOI	10.2210/pdb4haf/pdb
Related	3ave 4HAG
Descriptor	Ig gamma-2 chain C region, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose (3 entities in total)
Functional Keywords	immunoglobulin fold, immune system
Biological source	Homo sapiens (human)
Cellular location	Secreted: P01859
Total number of polymer chains	2
Total formula weight	51688.29
Authors	Teplyakov, A.,Malia, T.,Obmolova, G.,Zhao, Y.,Gilliland, G. (deposition date: 2012-09-26, release date: 2013-06-12, Last modification date: 2023-09-20)
Primary citation	Teplyakov, A.,Zhao, Y.,Malia, T.J.,Obmolova, G.,Gilliland, G.L. IgG2 Fc structure and the dynamic features of the IgG CH2-CH3 interface. Mol.Immunol., 56:131-139, 2013 Cited by PubMed: 23628091 DOI: 10.1016/j.molimm.2013.03.018 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.04 Å)

Structure validation