4H4F
Crystal structure of human chymotrypsin C (CTRC) bound to inhibitor eglin c from Hirudo medicinalis
Summary for 4H4F
| Entry DOI | 10.2210/pdb4h4f/pdb |
| Descriptor | Chymotrypsin-C, Eglin C, PHOSPHATE ION, ... (5 entities in total) |
| Functional Keywords | serine protease, protease inhibitor, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
| Biological source | Homo sapiens (human) More |
| Total number of polymer chains | 3 |
| Total formula weight | 37441.99 |
| Authors | Batra, J.,Soares, A.S.,Radisky, E.S. (deposition date: 2012-09-17, release date: 2013-02-27, Last modification date: 2013-04-24) |
| Primary citation | Batra, J.,Szabo, A.,Caulfield, T.R.,Soares, A.S.,Sahin-Toth, M.,Radisky, E.S. Long-range Electrostatic Complementarity Governs Substrate Recognition by Human Chymotrypsin C, a Key Regulator of Digestive Enzyme Activation. J.Biol.Chem., 288:9848-9859, 2013 Cited by PubMed: 23430245DOI: 10.1074/jbc.M113.457382 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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