4H1W

E1 structure of the (SR) Ca2+-ATPase in complex with Sarcolipin

Summary for 4H1W

• Entry DOI: 10.2210/pdb4h1w/pdb
• Related: 1T5S 1T5T 2C8K 3B9B
• Descriptor: SERCA1a, Sarcolipin, POTASSIUM ION, ... (6 entities in total)
• Functional Keywords: p-type atpase, ca2+ transport, sarcolipin, phospholamban, membrane protein, hydrolase-hydrolase regulator complex, hydrolase/hydrolase regulator
• Biological source: Oryctolagus cuniculus (European rabbit,Japanese white rabbit,domestic rabbit,rabbits); More
• Cellular location: Membrane ; Multi-pass membrane protein : B6CAM1; Sarcoplasmic reticulum membrane ; Single-pass membrane protein : P42532
• Total number of polymer chains: 2
• Total formula weight: 113996.34

Authors

Bublitz, M.,Winther, A.-M.L.,Karlsen, J.,Moller, J.V.,Hansen, J.B.,Buch-Pedersen, M.J.,Nissen, P. (deposition date: 2012-09-11, release date: 2013-03-06, Last modification date: 2024-02-28)

• Primary citation: Winther, A.M.,Bublitz, M.,Karlsen, J.L.,Moller, J.V.,Hansen, J.B.,Nissen, P.,Buch-Pedersen, M.J.; The sarcolipin-bound calcium pump stabilizes calcium sites exposed to the cytoplasm.; Nature, 495:265-269, 2013; PubMed: 23455424; DOI: 10.1038/nature11900

Experimental method

X-RAY DIFFRACTION (3.1 Å)