4GVH
Crystal structure of Salmonella typhimurium family 3 glycoside hydrolase (NagZ) covalently bound to 5-fluoro-GlcNAc.
Summary for 4GVH
Entry DOI | 10.2210/pdb4gvh/pdb |
Related | 4GVF 4GVG 4GVI |
Descriptor | Beta-hexosaminidase, 5-fluoro-N-acetyl-alpha-D-glucosamine, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ... (4 entities in total) |
Functional Keywords | tim-barrel, hydrolase, 5-f-glcnac, hydrolase-substrate complex, hydrolase/substrate |
Biological source | Salmonella enterica subsp. enterica serovar Typhimurium |
Cellular location | Cytoplasm (By similarity): Q8ZQ06 |
Total number of polymer chains | 2 |
Total formula weight | 78121.50 |
Authors | Bacik, J.P.,Mark, B.L. (deposition date: 2012-08-30, release date: 2012-12-19, Last modification date: 2020-07-29) |
Primary citation | Bacik, J.P.,Whitworth, G.E.,Stubbs, K.A.,Vocadlo, D.J.,Mark, B.L. Active Site Plasticity within the Glycoside Hydrolase NagZ Underlies a Dynamic Mechanism of Substrate Distortion. Chem.Biol., 19:1471-1482, 2012 Cited by PubMed: 23177201DOI: 10.1016/j.chembiol.2012.09.016 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.45 Å) |
Structure validation
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