4GU4
Crystal structure of the T1L reovirus attachment protein sigma1 in complex with alpha-2,3-sialyllactose
Summary for 4GU4
Entry DOI | 10.2210/pdb4gu4/pdb |
Related | 1KKE 3S6X 4GU3 |
Descriptor | Outer capsid protein sigma-1, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-4)-beta-D-glucopyranose, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose (3 entities in total) |
Functional Keywords | triple beta-spiral, beta-barrel, beta-spiral repeat, greek key motif, viral attachment protein, gm2 glycan alpha-2, 3-sialyllactose junctional adhesion molecule a, viral capsid, viral protein |
Biological source | Mammalian orthoreovirus 1 (T1L) |
Cellular location | Virion (By similarity): P04506 |
Total number of polymer chains | 3 |
Total formula weight | 75239.92 |
Authors | Reiss, K.,Stehle, T. (deposition date: 2012-08-29, release date: 2012-12-05, Last modification date: 2024-02-28) |
Primary citation | Reiss, K.,Stencel, J.E.,Liu, Y.,Blaum, B.S.,Reiter, D.M.,Feizi, T.,Dermody, T.S.,Stehle, T. The GM2 Glycan Serves as a Functional Coreceptor for Serotype 1 Reovirus. Plos Pathog., 8:e1003078-e1003078, 2012 Cited by PubMed: 23236285DOI: 10.1371/journal.ppat.1003078 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.5 Å) |
Structure validation
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