4GRV
The crystal structure of the neurotensin receptor NTS1 in complex with neurotensin (8-13)
Summary for 4GRV
Entry DOI | 10.2210/pdb4grv/pdb |
Descriptor | Neurotensin receptor type 1, lysozyme chimera, Neurotensin 8-13, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... (4 entities in total) |
Functional Keywords | g-protein coupled receptor, neurotensin receptor, g-protein, signaling protein-agonist complex, signaling protein/agonist |
Biological source | Rattus norvegicus (Rat, Bacteriaphage T4) More |
Cellular location | Cell membrane ; Multi- pass membrane protein : P20789 |
Total number of polymer chains | 2 |
Total formula weight | 58497.58 |
Authors | Noinaj, N.,White, J.F.,Shibata, Y.,Love, J.,Kloss, B.,Xu, F.,Gvozdenovic-Jeremic, J.,Shah, P.,Shiloach, J.,Tate, C.G.,Grisshammer, R. (deposition date: 2012-08-27, release date: 2012-10-17, Last modification date: 2023-09-13) |
Primary citation | White, J.F.,Noinaj, N.,Shibata, Y.,Love, J.,Kloss, B.,Xu, F.,Gvozdenovic-Jeremic, J.,Shah, P.,Shiloach, J.,Tate, C.G.,Grisshammer, R. Structure of the agonist-bound neurotensin receptor. Nature, 490:508-513, 2012 Cited by PubMed: 23051748DOI: 10.1038/nature11558 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.802 Å) |
Structure validation
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