4GRL
Crystal structure of a autoimmune TCR-MHC complex
Summary for 4GRL
Entry DOI | 10.2210/pdb4grl/pdb |
Related | 3PL6 4MAY |
Descriptor | MHC class II HLA-DQ-alpha chain, MHC class II antigen, TCR Hy.1B11 alpha chain, ... (6 entities in total) |
Functional Keywords | immune complex, peptide antigen presentation, multiple sclerosis, autoimmunity, immune system |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 4 |
Total formula weight | 97019.84 |
Authors | Sethi, D.K.,Wucherpfennig, K.W. (deposition date: 2012-08-25, release date: 2013-11-06, Last modification date: 2020-07-29) |
Primary citation | Sethi, D.K.,Gordo, S.,Schubert, D.A.,Wucherpfennig, K.W. Crossreactivity of a human autoimmune TCR is dominated by a single TCR loop. Nat Commun, 4:2623-2623, 2013 Cited by PubMed: 24136005DOI: 10.1038/ncomms3623 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.86 Å) |
Structure validation
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