3PL6
Structure of Autoimmune TCR Hy.1B11 in complex with HLA-DQ1 and MBP 85-99
Summary for 3PL6
Entry DOI | 10.2210/pdb3pl6/pdb |
Related | 1YMM |
Descriptor | MHC class II HLA-DQ-alpha chain, MHC class II HLA-DQ-beta chain, T-cell receptor alpha chain, ... (6 entities in total) |
Functional Keywords | tcr-mhc complex, immunoglobulin fold, immune receptor, membrane, immune system |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 4 |
Total formula weight | 98356.15 |
Authors | Sethi, D.K.,Wucherpfennig, K.W. (deposition date: 2010-11-13, release date: 2010-12-22, Last modification date: 2024-03-13) |
Primary citation | Sethi, D.K.,Schubert, D.A.,Anders, A.K.,Heroux, A.,Bonsor, D.A.,Thomas, C.P.,Sundberg, E.J.,Pyrdol, J.,Wucherpfennig, K.W. A highly tilted binding mode by a self-reactive T cell receptor results in altered engagement of peptide and MHC. J.Exp.Med., 208:91-102, 2011 Cited by PubMed: 21199956DOI: 10.1084/jem.20100725 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.55 Å) |
Structure validation
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