4GR7

The human W42R Gamma D-Crystallin Mutant Structure at 1.7A Resolution

Summary for 4GR7

• Entry DOI: 10.2210/pdb4gr7/pdb
• Descriptor: Gamma-crystallin D, PHOSPHATE ION (3 entities in total)
• Functional Keywords: cataract, greek key motif, structural protein, lens fiber cell
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 41306.87

Authors

Ji, F.,Jung, J.,Koharudin, L.M.I.,Gronenborn, A.M. (deposition date: 2012-08-24, release date: 2012-11-07, Last modification date: 2023-09-13)

• Primary citation: Ji, F.,Jung, J.,Koharudin, L.M.,Gronenborn, A.M.; The human W42R gamma D-crystallin mutant structure provides a link between congenital and age-related cataracts.; J.Biol.Chem., 288:99-109, 2013; PubMed: 23124202; DOI: 10.1074/jbc.M112.416354

Experimental method

X-RAY DIFFRACTION (1.7 Å)