4GIQ
Crystal Structure of mouse RANK bound to RANKL
Summary for 4GIQ
Entry DOI | 10.2210/pdb4giq/pdb |
Related | 1D0G 1D4V 1JTZ 3k51 3me2 3ME4 3QBQ |
Descriptor | Tumor necrosis factor ligand superfamily member 11, Tumor necrosis factor receptor superfamily member 11A, CHLORIDE ION, ... (6 entities in total) |
Functional Keywords | rank, odfr, activation-induced cytokine-receptor, tnfrsf11a, rankl, opgl, tnf-like cytokine, cysteine-rich domain, jelly-roll fold, protein binding-protein binding complex, protein binding/protein binding |
Biological source | Mus musculus (mouse) More |
Cellular location | Isoform 1: Cell membrane; Single-pass type II membrane protein. Isoform 2: Cell membrane; Single-pass type II membrane protein. Isoform 3: Cytoplasm. Tumor necrosis factor ligand superfamily member 11, soluble form: Secreted: O35235 Cell membrane ; Single-pass type I membrane protein : O35305 |
Total number of polymer chains | 2 |
Total formula weight | 38404.94 |
Authors | Nelson, C.A.,Wang, M.W.-H.,Fremont, D.H. (deposition date: 2012-08-08, release date: 2012-10-24, Last modification date: 2023-09-13) |
Primary citation | Nelson, C.A.,Warren, J.T.,Wang, M.W.,Teitelbaum, S.L.,Fremont, D.H. RANKL Employs Distinct Binding Modes to Engage RANK and the Osteoprotegerin Decoy Receptor. Structure, 20:1971-1982, 2012 Cited by PubMed: 23039992DOI: 10.1016/j.str.2012.08.030 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.7 Å) |
Structure validation
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