4GIQ

Crystal Structure of mouse RANK bound to RANKL

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Tumor necrosis factor ligand superfamily member 11	polymer	171	19056.4	1	UniProt (O35235) Pfam (PF00229)	Mus musculus (mouse)	Osteoclast differentiation factor, ODF, Osteoprotegerin ligand, OPGL, Receptor activator of nuclear factor kappa-B ligand, RANKL, TNF-related activation-induced cytokine, TRANCE, Tumor necrosis factor ligand superfamily member 11, membrane form, Tumor necrosis factor ligand superfamily member 11, soluble form
2	B (R)	Tumor necrosis factor receptor superfamily member 11A	polymer	174	19033.5	1	UniProt (O35305) Pfam (PF00020) Pfam (PF18278)	Mus musculus (mouse)	Osteoclast differentiation factor receptor, ODFR, Receptor activator of NF-KB
3	C, D (A)	CHLORIDE ION	non-polymer		35.5	2	Chemie (CL)
4	E (R)	SODIUM ION	non-polymer		23.0	1	Chemie (NA)
5	F (R)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	1	Chemie (NAG)
6	G, H (A, R)	water	water		18.0	81	Chemie (HOH)

Sequence modifications

A: 158 - 316 (UniProt: O35235)

PDB	External Database	Details
Gly 146	-	expression tag
Pro 147	-	expression tag
Leu 148	-	expression tag
Gly 149	-	expression tag
Ser 150	-	expression tag
Pro 151	-	expression tag
Glu 152	-	expression tag
Phe 153	-	expression tag
Pro 154	-	expression tag
Gly 155	-	expression tag
Arg 156	-	expression tag
Arg 157	-	expression tag

R: 1 - 168 (UniProt: O35305)

PDB	External Database	Details
Gly 169	-	expression tag
Ser 170	-	expression tag
Leu 171	-	expression tag
Val 172	-	expression tag
Pro 173	-	expression tag
Arg 174	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	38089.8
Non-Polymers*	Number of molecules	4
	Total formula weight	315.1
All*	Total formula weight	38404.9

*Water molecules are not included.