4G69

Structure of the Human Discs Large 1 PDZ2 - Adenomatous Polyposis Coli Cytoskeletal Polarity Complex

Summary for 4G69

Entry DOI	10.2210/pdb4g69/pdb
Descriptor	Disks large homolog 1, Adenomatous polyposis coli protein (3 entities in total)
Functional Keywords	pdz, maguk, polarity, adenomatous polyposis coli, tetramethylrhodamine, adherens junction, membrane protein-signaling protein complex, membrane protein/signaling protein
Biological source	Homo sapiens (human) More
Cellular location	Membrane ; Peripheral membrane protein : Q12959 Cell junction, adherens junction : P25054
Total number of polymer chains	2
Total formula weight	11807.57
Authors	Slep, K.C. (deposition date: 2012-07-18, release date: 2012-12-12, Last modification date: 2023-09-13)
Primary citation	Slep, K.C. Structure of the Human Discs Large 1 PDZ2- Adenomatous Polyposis Coli Cytoskeletal Polarity Complex: Insight into Peptide Engagement and PDZ Clustering. Plos One, 7:e50097-e50097, 2012 Cited by PubMed: 23185543 DOI: 10.1371/journal.pone.0050097 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation