4G5H
Crystal structure of capsular polysaccharide synthesizing enzyme CapE from Staphylococcus aureus in complex with by-product
Summary for 4G5H
Entry DOI | 10.2210/pdb4g5h/pdb |
Related | 3VVB 3VVC |
Descriptor | Capsular polysaccharide synthesis enzyme Cap8E, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, [(2R,3R,4R,6R)-3-acetamido-6-methyl-4-oxidanyl-5-oxidanylidene-oxan-2-yl] [[(2R,3S,4R,5R)-5-[2,4-bis(oxidanylidene)pyrimidin-1-yl]-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] hydrogen phosphate, ... (6 entities in total) |
Functional Keywords | rossmann fold, short-chain dehydrogenase/reductase, capsular polysaccharide synthesis, oxidase, epimerase, lyase |
Biological source | Staphylococcus aureus |
Total number of polymer chains | 1 |
Total formula weight | 43545.94 |
Authors | Miyafusa, T.,Caaveiro, J.M.M.,Tanaka, Y.,Tsumoto, K. (deposition date: 2012-07-18, release date: 2013-08-28, Last modification date: 2024-03-20) |
Primary citation | Miyafusa, T.,Caaveiro, J.M.,Tanaka, Y.,Tsumoto, K. Dynamic elements govern the catalytic activity of CapE, a capsular polysaccharide-synthesizing enzyme from Staphylococcus aureus. Febs Lett., 587:3824-3830, 2013 Cited by PubMed: 24157361DOI: 10.1016/j.febslet.2013.10.009 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.88 Å) |
Structure validation
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