4FR6

tRNA-Guanine Transglycosylase cocrystallized with pyridyl-alkine-substituted lin-benzoguanine ligand

Summary for 4FR6

• Entry DOI: 10.2210/pdb4fr6/pdb
• Related: 3EOS 3S1G 3V0Y 4FPS 4FR1 4FSA
• Descriptor: Queuine tRNA-ribosyltransferase, ZINC ION, 6-amino-2-(methylamino)-4-[2-({[trans-4-(pyridin-3-ylethynyl)cyclohexyl]methyl}amino)ethyl]-1,7-dihydro-8H-imidazo[4,5-g]quinazolin-8-one, ... (4 entities in total)
• Functional Keywords: tim barrel, glycosyltransferase, queuosine, biosynthesis, transferase, trna processing, trna, transferase-transferase inhibitor complex, transferase/transferase inhibitor
• Biological source: Zymomonas mobilis subsp. mobilis
• Total number of polymer chains: 1
• Total formula weight: 43461.68

Authors

Immekus, F.,Klebe, G. (deposition date: 2012-06-26, release date: 2013-07-24, Last modification date: 2023-09-13)

• Primary citation: Immekus, F.,Barandun, L.J.,Betz, M.,Debaene, F.,Petiot, S.,Sanglier-Cianferani, S.,Diederich, F.,Klebe, G.; Studies on TGT homodimer interface; To be Published,

Experimental method

X-RAY DIFFRACTION (1.59 Å)