4FAF

Substrate CA/p2 in Complex with a Human Immunodeficiency Virus Type 1 Protease Variant

Summary for 4FAF

Entry DOI	10.2210/pdb4faf/pdb
Related	1TW7 3OQ7 4FAE
Descriptor	HIV-1 protease, substrate CA/p2 peptide (3 entities in total)
Functional Keywords	protease, viral protein
Biological source	Human immunodeficiency virus 1
Total number of polymer chains	3
Total formula weight	22405.33
Authors	Wang, Y.,Dewdney, T.G.,Liu, Z.,Reiter, S.J.,Brunzelle, J.S.,Kovari, I.A.,Kovari, L.C. (deposition date: 2012-05-22, release date: 2012-08-29, Last modification date: 2023-07-26)
Primary citation	Wang, Y.,Dewdney, T.G.,Liu, Z.,Reiter, S.J.,Brunzelle, J.S.,Kovari, I.A.,Kovari, L.C. Higher Desolvation Energy Reduces Molecular Recognition in Multi-Drug Resistant HIV-1 Protease. Biology (Basel), 1:81-93, 2012 Cited by PubMed: 24832048 DOI: 10.3390/biology1010081 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.1 Å)

Structure validation