4F9C
Human CDC7 kinase in complex with DBF4 and XL413
Summary for 4F9C
Entry DOI | 10.2210/pdb4f9c/pdb |
Related | 4F99 4F9A 4F9B |
Descriptor | Cell division cycle 7-related protein kinase, Protein DBF4 homolog A, 8-chloro-2-[(2S)-pyrrolidin-2-yl][1]benzofuro[3,2-d]pyrimidin-4(3H)-one, ... (5 entities in total) |
Functional Keywords | ser/thr protein kinase, transferase, phosphorylation, cell cycle, cell division, mitosis, s phase, serine/threonine-protein kinase, dbf4-dependent kinase, ddk, atp-binding, nucleotide-binding, zinc-binding, nucleus, transferase-transferase inhibitor complex, transferase/transferase inhibitor |
Biological source | Homo sapiens (human) More |
Cellular location | Nucleus: O00311 Q9UBU7 |
Total number of polymer chains | 2 |
Total formula weight | 57912.37 |
Authors | Hughes, S.,Cherepanov, P. (deposition date: 2012-05-18, release date: 2012-10-31, Last modification date: 2024-02-28) |
Primary citation | Hughes, S.,Elustondo, F.,Di Fonzo, A.,Leroux, F.G.,Wong, A.C.,Snijders, A.P.,Matthews, S.J.,Cherepanov, P. Crystal structure of human CDC7 kinase in complex with its activator DBF4. Nat.Struct.Mol.Biol., 19:1101-1107, 2012 Cited by PubMed: 23064647DOI: 10.1038/nsmb.2404 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.08 Å) |
Structure validation
Download full validation report