4F7B
Structure of the lysosomal domain of limp-2
Summary for 4F7B
Entry DOI | 10.2210/pdb4f7b/pdb |
Descriptor | Lysosome membrane protein 2, DI(HYDROXYETHYL)ETHER, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (10 entities in total) |
Functional Keywords | structural genomics, structural genomics consortium, sgc, scavenger receptor, lipid transport, endocytosis, atherosclerosis, lipoprotein, cell adhesion |
Biological source | Homo sapiens (human) |
Cellular location | Lysosome membrane; Multi-pass membrane protein: Q14108 |
Total number of polymer chains | 6 |
Total formula weight | 312713.52 |
Authors | Neculai, D.,Ravichandran, M.,Seitova, A.,Neculai, M.,Pizzaro, J.C.,Bountra, C.,Edwards, A.M.,Arrowsmith, C.H.,Dhe-Paganon, D.,Structural Genomics Consortium (SGC) (deposition date: 2012-05-15, release date: 2013-10-09, Last modification date: 2020-07-29) |
Primary citation | Neculai, D.,Schwake, M.,Ravichandran, M.,Zunke, F.,Collins, R.F.,Peters, J.,Neculai, M.,Plumb, J.,Loppnau, P.,Pizarro, J.C.,Seitova, A.,Trimble, W.S.,Saftig, P.,Grinstein, S.,Dhe-Paganon, S. Structure of LIMP-2 provides functional insights with implications for SR-BI and CD36. Nature, 504:172-176, 2013 Cited by PubMed: 24162852DOI: 10.1038/nature12684 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3 Å) |
Structure validation
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