4F7B
Structure of the lysosomal domain of limp-2
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | Lysosome membrane protein 2 | polymer | 423 | 48606.6 | 6 | UniProt (Q14108) Pfam (PF01130) | Homo sapiens (human) | 85 kDa lysosomal membrane sialoglycoprotein, LGP85, CD36 antigen-like 2, Lysosome membrane protein II, LIMP II, Scavenger receptor class B member 2 |
| 2 | BA, CA, G, X (b, c, G, X) | alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 748.7 | 4 | In PDB GlyTouCan (G81315DD) | |||
| 3 | H, T (H, T) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 951.9 | 2 | In PDB GlyTouCan (G10133VD) | |||
| 4 | AA, EA, FA, I, K... (a, e, f, I, K...) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 8 | In PDB GlyTouCan (G15407YE) | |||
| 5 | GA, J, L, O, Q... (g, J, L, O, Q...) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 10 | In PDB GlyTouCan (G42666HT) | |||
| 6 | M, Y (M, Y) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1114.0 | 2 | In PDB GlyTouCan (G61751GZ) | |||
| 7 | DA (d) | alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 910.8 | 1 | In PDB GlyTouCan (G22768VO) | |||
| 8 | AB, BB, HA, IA, JA... (F, A, B, C, D...) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 15 | Chemie (NAG) | |||
| 9 | CB, KA, QA, TA, VA... (F, A, B, C, D...) | PHOSPHATE ION | non-polymer | 95.0 | 6 | Chemie (PO4) | |||
| 10 | DB, LA (F, A) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 2 | Chemie (PEG) |
Sequence modifications
A, B, C, D, E, F: 35 - 430 (UniProt: Q14108)
| PDB | External Database | Details |
|---|---|---|
| Ala 8 | - | expression tag |
| Ala 9 | - | expression tag |
| Pro 10 | - | expression tag |
| Glu 11 | - | expression tag |
| His 12 | - | expression tag |
| His 13 | - | expression tag |
| His 14 | - | expression tag |
| His 15 | - | expression tag |
| His 16 | - | expression tag |
| His 17 | - | expression tag |
| Asp 18 | - | expression tag |
| Tyr 19 | - | expression tag |
| Asp 20 | - | expression tag |
| Ile 21 | - | expression tag |
| Pro 22 | - | expression tag |
| Thr 23 | - | expression tag |
| Thr 24 | - | expression tag |
| Glu 25 | - | expression tag |
| Asn 26 | - | expression tag |
| Leu 27 | - | expression tag |
| Tyr 28 | - | expression tag |
| Phe 29 | - | expression tag |
| Gln 30 | - | expression tag |
| Gly 31 | - | expression tag |
| Ala 32 | - | expression tag |
| Met 33 | - | expression tag |
| Asp 34 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 291639.7 | |
| Branched | Number of molecules | 27 |
| Total formula weight | 16973.7 | |
| Non-Polymers* | Number of molecules | 23 |
| Total formula weight | 4100.2 | |
| All* | Total formula weight | 312713.5 |
