4F2M
Crystal structure of a TGEV coronavirus Spike fragment in complex with the TGEV neutralizing monoclonal antibody 1AF10
Summary for 4F2M
Entry DOI | 10.2210/pdb4f2m/pdb |
Related | 4F5C |
Descriptor | monoclonal antibody 1AF10, heavy chain, monoclonal antibody 1AF10, light chain, Spike protein, ... (7 entities in total) |
Functional Keywords | beta-barrel, immunoglobulin, virus entry, virus neutralization, cellular receptor, aminopeptidase n, glycosylation, virus membrane, viral protein-immune system complex, viral protein/immune system |
Biological source | Mus musculus (mouse) More |
Total number of polymer chains | 6 |
Total formula weight | 142677.27 |
Authors | Reguera, J.,Santiago, C.,Mudgal, G.,Ordono, D.,Enjuanes, L.,Casasnovas, J.M. (deposition date: 2012-05-08, release date: 2012-08-22, Last modification date: 2020-07-29) |
Primary citation | Reguera, J.,Santiago, C.,Mudgal, G.,Ordono, D.,Enjuanes, L.,Casasnovas, J.M. Structural bases of coronavirus attachment to host aminopeptidase N and its inhibition by neutralizing antibodies. Plos Pathog., 8:e1002859-e1002859, 2012 Cited by PubMed: 22876187DOI: 10.1371/journal.ppat.1002859 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3 Å) |
Structure validation
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