4EZ7
CDK2 in complex with staurosporine and 2 molecules of 8-anilino-1-naphthalene sulfonic acid
Summary for 4EZ7
Entry DOI | 10.2210/pdb4ez7/pdb |
Related | 4ERW 4EZ3 |
Descriptor | Cyclin-dependent kinase 2, STAUROSPORINE, 8-ANILINO-1-NAPHTHALENE SULFONATE, ... (5 entities in total) |
Functional Keywords | protein kinase, ans, transferase-antibiotic complex, transferase/antibiotic |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm, cytoskeleton, centrosome: P24941 |
Total number of polymer chains | 1 |
Total formula weight | 36074.84 |
Authors | Alam, R.,Martin, M.P.,Zhu, J.-Y.,Schonbrunn, E. (deposition date: 2012-05-02, release date: 2012-08-22, Last modification date: 2023-09-13) |
Primary citation | Martin, M.P.,Alam, R.,Betzi, S.,Ingles, D.J.,Zhu, J.Y.,Schonbrunn, E. A Novel Approach to the Discovery of Small-Molecule Ligands of CDK2. Chembiochem, 13:2128-2136, 2012 Cited by PubMed: 22893598DOI: 10.1002/cbic.201200316 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.49 Å) |
Structure validation
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