4EZ7
CDK2 in complex with staurosporine and 2 molecules of 8-anilino-1-naphthalene sulfonic acid
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Cyclin-dependent kinase 2 | polymer | 306 | 34761.3 | 1 | UniProt (P24941) Pfam (PF00069) | Homo sapiens (human) | CDK2, Cell division protein kinase 2, p33 protein kinase |
| 2 | B (A) | STAUROSPORINE | non-polymer | 466.5 | 1 | Chemie (STU) | |||
| 3 | C, D (A) | 8-ANILINO-1-NAPHTHALENE SULFONATE | non-polymer | 299.3 | 2 | Chemie (2AN) | |||
| 4 | E, F, G, H (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 4 | Chemie (EDO) | |||
| 5 | I (A) | water | water | 18.0 | 40 | Chemie (HOH) |
Sequence modifications
A: 1 - 298 (UniProt: P24941)
| PDB | External Database | Details |
|---|---|---|
| Gly -7 | - | expression tag |
| Pro -6 | - | expression tag |
| Leu -5 | - | expression tag |
| Gly -4 | - | expression tag |
| Ser -3 | - | expression tag |
| Pro -2 | - | expression tag |
| Glu -1 | - | expression tag |
| Phe 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 34761.3 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 1313.5 | |
| All* | Total formula weight | 36074.8 |
