4EOJ

Thr 160 phosphorylated CDK2 H84S, Q85M, K89D - human cyclin A3 complex with ATP

Summary for 4EOJ

Entry DOI	10.2210/pdb4eoj/pdb
Related	4EOI 4EOK 4EOL 4EOM 4EON 4EOO 4EOP 4EOQ 4EOR 4EOS
Descriptor	Cyclin-dependent kinase 2, Cyclin-A2, ADENOSINE-5'-TRIPHOSPHATE, ... (6 entities in total)
Functional Keywords	protein kinase, cell cycle, complex, phosphorylation, transferase
Biological source	Homo sapiens (human) More
Cellular location	Cytoplasm, cytoskeleton, centrosome: P24941 Nucleus: P20248
Total number of polymer chains	4
Total formula weight	129225.44
Authors	Echalier, A.,Cot, E.,Camasses, A.,Hodimont, E.,Hoh, F.,Sheinerman, F.,Krasinska, L.,Fisher, D. (deposition date: 2012-04-14, release date: 2013-02-06)
Primary citation	Echalier, A.,Cot, E.,Camasses, A.,Hodimont, E.,Hoh, F.,Jay, P.,Sheinerman, F.,Krasinska, L.,Fisher, D. An integrated chemical biology approach provides insight into Cdk2 functional redundancy and inhibitor sensitivity. Chem.Biol., 19:1028-1040, 2012 Cited by PubMed: 22921070 DOI: 10.1016/j.chembiol.2012.06.015 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.65 Å)

Structure validation