4EB1
Hyperstable in-frame insertion variant of antithrombin
Summary for 4EB1
Entry DOI | 10.2210/pdb4eb1/pdb |
Related | 1E04 |
Descriptor | Antithrombin-III, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total) |
Functional Keywords | serpin, hydrolase inhibitor, blood clotting |
Biological source | Homo sapiens (human) More |
Cellular location | Secreted, extracellular space: P01008 P01008 |
Total number of polymer chains | 2 |
Total formula weight | 100319.26 |
Authors | Martinez-Martinez, I.,Johnson, D.J.D.,Yamasaki, M.,Corral, J.,Huntington, J.A. (deposition date: 2012-03-23, release date: 2012-07-18, Last modification date: 2023-09-13) |
Primary citation | Martinez-Martinez, I.,Johnson, D.J.,Yamasaki, M.,Navarro-Fernandez, J.,Ordonez, A.,Vicente, V.,Huntington, J.A.,Corral, J. Type II antithrombin deficiency caused by a large in-frame insertion: structural, functional and pathological relevance. J.Thromb.Haemost., 10:1859-1866, 2012 Cited by PubMed: 22758787DOI: 10.1111/j.1538-7836.2012.04839.x PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.8 Å) |
Structure validation
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