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4EB1

Hyperstable in-frame insertion variant of antithrombin

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(I)
Antithrombin-IIIpolymer44049927.01UniProt (P01008)
Pfam (PF00079)
Homo sapiens (human)ATIII, Serpin C1
2B
(L)
Antithrombin-IIIpolymer43249101.01UniProt (P01008)
Pfam (PF00079)
Homo sapiens (human)latent alpha antithrombin, ATIII, Serpin C1
3C, D
(A, B)
2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranosebranched424.42In PDB
GlyTouCan (G42666HT)
4E, F
(I)
2-acetamido-2-deoxy-beta-D-glucopyranosenon-polymer221.22Chemie (NAG)
5G, H
(I, L)
waterwater18.027Chemie (HOH)
Sequence modifications
I: 1 - 208 (UniProt: P01008)
PDBExternal DatabaseDetails
Ala 137Ser 169engineered mutation
I: 219 - 440 (UniProt: P01008)
PDBExternal DatabaseDetails
Val 209-insertion
Leu 210-insertion
Val 211-insertion
Leu 212-insertion
Val 213-insertion
Asn 214-insertion
Thr 215-insertion
Arg 216-insertion
Thr 217-insertion
Ser 218-insertion
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight99028.0
BranchedNumber of molecules2
Total formula weight848.8
Non-Polymers*Number of molecules2
Total formula weight442.4
All*Total formula weight100319.3
*Water molecules are not included.

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PDB entries from 2025-07-23

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