4E84
Crystal Structure of Burkholderia cenocepacia HldA
Summary for 4E84
Entry DOI | 10.2210/pdb4e84/pdb |
Related | 4E8W 4E8Y 4E8Z |
Descriptor | D-beta-D-heptose 7-phosphate kinase, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, 7-O-phosphono-D-glycero-beta-D-manno-heptopyranose, ... (9 entities in total) |
Functional Keywords | lps-heptose biosynthesis, beta-clasp dimerization region, pfkb carbohydrate kinase, phosphorylation, transferase |
Biological source | Burkholderia cenocepacia |
Total number of polymer chains | 2 |
Total formula weight | 79550.15 |
Authors | Lee, T.-W.,Junop, M.S. (deposition date: 2012-03-19, release date: 2012-12-26, Last modification date: 2020-07-29) |
Primary citation | Lee, T.W.,Verhey, T.B.,Antiperovitch, P.A.,Atamanyuk, D.,Desroy, N.,Oliveira, C.,Denis, A.,Gerusz, V.,Drocourt, E.,Loutet, S.A.,Hamad, M.A.,Stanetty, C.,Andres, S.N.,Sugiman-Marangos, S.,Kosma, P.,Valvano, M.A.,Moreau, F.,Junop, M.S. Structural-functional studies of Burkholderia cenocepacia D-glycero-beta-D-manno-heptose 7-phosphate kinase (HldA) and characterization of inhibitors with antibiotic adjuvant and antivirulence properties. J.Med.Chem., 56:1405-1417, 2013 Cited by PubMed: 23256532DOI: 10.1021/jm301483h PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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