4DZ8
human IgG1 Fc fragment Heterodimer
Summary for 4DZ8
Entry DOI | 10.2210/pdb4dz8/pdb |
Descriptor | Ig gamma-1 chain C region, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total) |
Functional Keywords | fc fragment, antibody, immune system |
Biological source | Homo sapiens (human) More |
Cellular location | Secreted: P01857 P01857 |
Total number of polymer chains | 2 |
Total formula weight | 53257.61 |
Authors | Strop, P. (deposition date: 2012-02-29, release date: 2012-08-01, Last modification date: 2020-07-29) |
Primary citation | Strop, P.,Ho, W.H.,Boustany, L.M.,Abdiche, Y.N.,Lindquist, K.C.,Farias, S.E.,Rickert, M.,Appah, C.T.,Pascua, E.,Radcliffe, T.,Sutton, J.,Chaparro-Riggers, J.,Chen, W.,Casas, M.G.,Chin, S.M.,Wong, O.K.,Liu, S.H.,Vergara, G.,Shelton, D.,Rajpal, A.,Pons, J. Generating Bispecific Human IgG1 and IgG2 Antibodies from Any Antibody Pair. J.Mol.Biol., 420:204-219, 2012 Cited by PubMed: 22543237DOI: 10.1016/j.jmb.2012.04.020 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.91 Å) |
Structure validation
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