4DY0
Crystal structure of native protease nexin-1 with heparin
Summary for 4DY0
Entry DOI | 10.2210/pdb4dy0/pdb |
Descriptor | Glia-derived nexin, 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid, SULFATE ION, ... (5 entities in total) |
Functional Keywords | serpin, protease inhibitor, thrombin, cell surface, hydrolase inhibitor |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 2 |
Total formula weight | 84994.90 |
Authors | Huntington, J.A.,Li, W. (deposition date: 2012-02-28, release date: 2012-08-15, Last modification date: 2024-03-13) |
Primary citation | Li, W.,Huntington, J.A. Crystal structures of protease nexin-1 in complex with heparin and thrombin suggest a 2-step recognition mechanism. Blood, 120:459-467, 2012 Cited by PubMed: 22618708DOI: 10.1182/blood-2012-03-415869 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.35 Å) |
Structure validation
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