4DFR
CRYSTAL STRUCTURES OF ESCHERICHIA COLI AND LACTOBACILLUS CASEI DIHYDROFOLATE REDUCTASE REFINED AT 1.7 ANGSTROMS RESOLUTION. I. GENERAL FEATURES AND BINDING OF METHOTREXATE
Replaces: 2DFRSummary for 4DFR
Entry DOI | 10.2210/pdb4dfr/pdb |
Descriptor | DIHYDROFOLATE REDUCTASE, CHLORIDE ION, METHOTREXATE, ... (5 entities in total) |
Functional Keywords | oxido-reductase, oxidoreductase |
Biological source | Escherichia coli |
Total number of polymer chains | 2 |
Total formula weight | 37060.65 |
Authors | Filman, D.J.,Matthews, D.A.,Bolin, J.T.,Kraut, J. (deposition date: 1982-06-25, release date: 1982-10-21, Last modification date: 2024-02-28) |
Primary citation | Bolin, J.T.,Filman, D.J.,Matthews, D.A.,Hamlin, R.C.,Kraut, J. Crystal structures of Escherichia coli and Lactobacillus casei dihydrofolate reductase refined at 1.7 A resolution. I. General features and binding of methotrexate. J.Biol.Chem., 257:13650-13662, 1982 Cited by PubMed: 6815178PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.7 Å) |
Structure validation
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