4CLM
Structure of Salmonella typhi type I dehydroquinase irreversibly inhibited with a 1,3,4-trihydroxyciclohexane-1-carboxylic acid derivative
Summary for 4CLM
Entry DOI | 10.2210/pdb4clm/pdb |
Related | 4CKW 4CKX 4CKY 4CKZ 4CL0 |
Descriptor | 3-DEHYDROQUINATE DEHYDRATASE, CHLORIDE ION, LITHIUM ION, ... (5 entities in total) |
Functional Keywords | type i dehydroquinase, lyase, inhibitor, shikimis acid pathway, substrate specificity |
Biological source | SALMONELLA ENTERICA SUBSP. ENTERICA SEROVAR TYPHI |
Total number of polymer chains | 2 |
Total formula weight | 55665.48 |
Authors | Otero, J.M.,Llamas-Saiz, A.L.,Tizon, L.,Maneiro, M.,Lence, E.,Poza, S.,Lamb, H.,Hawkins, A.R.,Blanco, B.,Sedes, A.,Peon, A.,Gonzalez-Bello, C.,van Raaij, M.J. (deposition date: 2014-01-15, release date: 2014-11-05, Last modification date: 2023-12-20) |
Primary citation | Tizon, L.,Maneiro, M.,Peon, A.,Otero, J.M.,Lence, E.,Poza, S.,van Raaij, M.J.,Thompson, P.,Hawkins, A.R.,Gonzalez-Bello, C. Irreversible covalent modification of type I dehydroquinase with a stable Schiff base. Org. Biomol. Chem., 13:706-716, 2015 Cited by PubMed: 25370445DOI: 10.1039/c4ob01782j PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.4 Å) |
Structure validation
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