4C4M
Crystal structure of the Sonic Hedgehog-chondroitin-4-sulphate complex
Summary for 4C4M
Entry DOI | 10.2210/pdb4c4m/pdb |
Related | 4C4N |
Descriptor | SONIC HEDGEHOG PROTEIN, beta-D-glucopyranuronic acid-(1-3)-2-acetamido-2-deoxy-4-O-sulfo-beta-D-galactopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-3)-2-acetamido-2-deoxy-4-O-sulfo-beta-D-galactopyranose, ZINC ION, ... (6 entities in total) |
Functional Keywords | signaling protein, hedgehog signalling, morphogens, heparan sulphate proteoglycans, glycosaminoglycans |
Biological source | MUS MUSCULUS (HOUSE MOUSE) |
Total number of polymer chains | 1 |
Total formula weight | 19909.40 |
Authors | Whalen, D.M.,Malinauskas, T.,Gilbert, R.J.C.,Siebold, C. (deposition date: 2013-09-05, release date: 2013-10-02, Last modification date: 2024-05-08) |
Primary citation | Whalen, D.M.,Malinauskas, T.,Gilbert, R.J.C.,Siebold, C. Structural Insights Into Proteoglycan-Shaped Hedgehog Signaling. Proc.Natl.Acad.Sci.USA, 110:16420-, 2013 Cited by PubMed: 24062467DOI: 10.1073/PNAS.1310097110 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.74 Å) |
Structure validation
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