4C4M
Crystal structure of the Sonic Hedgehog-chondroitin-4-sulphate complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | SONIC HEDGEHOG PROTEIN | polymer | 164 | 18768.0 | 1 | UniProt (Q62226) Pfam (PF01085) | MUS MUSCULUS (HOUSE MOUSE) | SHH, HHG-1 |
| 2 | B (B) | beta-D-glucopyranuronic acid-(1-3)-2-acetamido-2-deoxy-4-O-sulfo-beta-D-galactopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-3)-2-acetamido-2-deoxy-4-O-sulfo-beta-D-galactopyranose | branched | 936.8 | 1 | In PDB GlyTouCan (G44097BM) | |||
| 3 | C (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 4 | D, E (A) | CALCIUM ION | non-polymer | 40.1 | 2 | Chemie (CA) | |||
| 5 | F (A) | ACETATE ION | non-polymer | 59.0 | 1 | Chemie (ACT) | |||
| 6 | G (A) | water | water | 18.0 | 129 | Chemie (HOH) |
Sequence modifications
A: 40 - 195 (UniProt: Q62226)
| PDB | External Database | Details |
|---|---|---|
| Met 38 | - | expression tag |
| Ala 39 | - | expression tag |
| His 196 | - | expression tag |
| His 197 | - | expression tag |
| His 198 | - | expression tag |
| His 199 | - | expression tag |
| His 200 | - | expression tag |
| His 201 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 18768.0 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 936.8 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 204.6 | |
| All* | Total formula weight | 19909.4 |
