4C4D
Covalent glycosyl-enzyme intermediate of Hypocrea jecorina Cel7a E217Q mutant trapped using DNP-2-deoxy-2-fluoro-cellotrioside
Summary for 4C4D
Entry DOI | 10.2210/pdb4c4d/pdb |
Related | 4C4C |
Related PRD ID | PRD_900005 |
Descriptor | CELLULOSE 1,4-BETA-CELLOBIOSIDASE, beta-D-glucopyranose-(1-4)-beta-D-glucopyranose, beta-D-glucopyranose-(1-4)-beta-D-glucopyranose-(1-4)-beta-D-glucopyranose-(1-4)-beta-D-glucopyranose-(1-4)-beta-D-glucopyranose-(1-4)-2-deoxy-2-fluoro-alpha-D-glucopyranose, ... (7 entities in total) |
Functional Keywords | hydrolase, glycoside hydrolase, cellobiohydrolase, cellulase. |
Biological source | TRICHODERMA REESEI |
Total number of polymer chains | 1 |
Total formula weight | 48128.24 |
Authors | Haddad-Momeni, M.,Mackenzie, L.,Sandgren, M.,Withers, S.G.,Stahlberg, J. (deposition date: 2013-09-05, release date: 2014-01-08, Last modification date: 2023-12-20) |
Primary citation | Knott, B.C.,Haddad Momeni, M.,Crowley, M.F.,Mackenzie, L.F.,Gotz, A.W.,Sandgren, M.,Withers, S.G.,Stahlberg, J.,Beckham, G.T. The Mechanism of Cellulose Hydrolysis by a Two-Step, Retaining Cellobiohydrolase Elucidated by Structural and Transition Path Sampling Studies. J.Am.Chem.Soc., 136:321-, 2014 Cited by PubMed: 24341799DOI: 10.1021/JA410291U PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.32 Å) |
Structure validation
Download full validation report