4C2V
Aurora B kinase in complex with the specific inhibitor Barasertib
Summary for 4C2V
Entry DOI | 10.2210/pdb4c2v/pdb |
Related | 4C2W |
Descriptor | AURORA KINASE B-A, INNER CENTROMERE PROTEIN A, 2-[5-[[7-[3-[ethyl(2-hydroxyethyl)amino]propoxy]quinazolin-4-yl]amino]-1H-pyrazol-3-yl]-N-(3-fluorophenyl)ethanamide, ... (4 entities in total) |
Functional Keywords | transferase-cell cycle complex, azd1152, transferase/cell cycle |
Biological source | XENOPUS LAEVIS (AFRICAN CLAWED FROG) More |
Cellular location | Nucleus: Q6DE08 Chromosome, centromere: O13024 |
Total number of polymer chains | 4 |
Total formula weight | 78464.47 |
Authors | |
Primary citation | Sessa, F.,Villa, F. Structure of Aurora B-Incenp in Complex with Barasertib Reveals a Potential Transinhibitory Mechanism Acta Crystallogr.,Sect.F, 70:294-, 2014 Cited by PubMed: 24598913DOI: 10.1107/S2053230X14002118 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.49 Å) |
Structure validation
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