4C2V
Aurora B kinase in complex with the specific inhibitor Barasertib
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | AURORA KINASE B-A | polymer | 285 | 33650.9 | 2 | UniProt (Q6DE08) Pfam (PF00069) In PDB | XENOPUS LAEVIS (AFRICAN CLAWED FROG) | AURORA/IPL1-RELATED KINASE 2-A, AIRK2-A, XAIRK2-A, SERINE/THREONINE-PROTEIN KINASE 12-A, SERINE/THREONINE-PROTEIN KINASE AURORA-B-A, XAURORA-B |
| 2 | C, D | INNER CENTROMERE PROTEIN A | polymer | 44 | 5073.8 | 2 | UniProt (O13024) Pfam (PF03941) In PDB | XENOPUS LAEVIS (AFRICAN CLAWED FROG) | XL-INCENP, XINC, XINCENP, MITOTIC PHOSPHOPROTEIN 130 |
| 3 | A, B | 2-[5-[[7-[3-[ethyl(2-hydroxyethyl)amino]propoxy]quinazolin-4-yl]amino]-1H-pyrazol-3-yl]-N-(3-fluorophenyl)ethanamide | non-polymer | 507.6 | 2 | Chemie (YJA) | |||
| 4 | water | water | 18.0 | 595 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 77449.4 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 1015.1 | |
| All* | Total formula weight | 78464.5 |
