4BD8

Bax domain swapped dimer induced by BimBH3 with CHAPS

Summary for 4BD8

Entry DOI	10.2210/pdb4bd8/pdb
Related	4BD2 4BD6 4BD7 4BDU
Descriptor	APOPTOSIS REGULATOR BAX, PRASEODYMIUM ION, 1,2-ETHANEDIOL, ... (4 entities in total)
Functional Keywords	apoptosis, programmed cell death
Biological source	HOMO SAPIENS (HUMAN)
Cellular location	Isoform Alpha: Mitochondrion membrane; Single-pass membrane protein. Isoform Beta: Cytoplasm. Isoform Gamma: Cytoplasm. Isoform Delta: Cytoplasm (Potential): Q07812
Total number of polymer chains	4
Total formula weight	77509.20
Authors	Czabotar, P.E.,Westphal, D.,Adams, J.M.,Colman, P.M. (deposition date: 2012-10-05, release date: 2013-02-13)
Primary citation	Czabotar, P.E.,Westphal, D.,Dewson, G.,Ma, S.,Hockings, C.,Fairlie, W.D.,Lee, E.F.,Yao, S.,Robin, A.Y.,Smith, B.J.,Huang, D.C.,Kluck, R.M.,Adams, J.M.,Colman, P.M. Bax Crystal Structures Reveal How Bh3 Domains Activate Bax and Nucleate its Oligomerization to Induce Apoptosis. Cell(Cambridge,Mass.), 152:519-, 2013 Cited by PubMed: 23374347 DOI: 10.1016/J.CELL.2012.12.031 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.22 Å)

Structure validation