4A99

STRUCTURE OF THE TETRACYCLINE DEGRADING MONOOXYGENASE TETX IN COMPLEX WITH MINOCYCLINE

Summary for 4A99

Entry DOI	10.2210/pdb4a99/pdb
Related	2XDO 2XYO 2Y6Q 2Y6R
Descriptor	TETX2 PROTEIN, FLAVIN-ADENINE DINUCLEOTIDE, (4S,4AS,5AR,12AS)-4,7-BIS(DIMETHYLAMINO)-3,10,12,12A-TETRAHYDROXY-1,11-DIOXO-1,4,4A,5,5A,6,11,12A-OCTAHYDROTETRACENE-2- CARBOXAMIDE, ... (5 entities in total)
Functional Keywords	flavoprotein, tetracycline degradation, monooxygenase, flavin
Biological source	BACTEROIDES THETAIOTAOMICRON
Total number of polymer chains	4
Total formula weight	186576.22
Authors	Volkers, G.,Palm, G.J.,Weiss, M.S.,Hinrichs, W. (deposition date: 2011-11-25, release date: 2012-12-12, Last modification date: 2023-12-20)
Primary citation	Volkers, G.,Damas, J.M.,Palm, G.J.,Panjikar, S.,Soares, C.M.,Hinrichs, W. Putative Dioxygen-Binding Sites and Recognition of Tigecycline and Minocycline in the Tetracycline-Degrading Monooxygenase Tetx Acta Crystallogr.,Sect.D, 69:1758-, 2013 Cited by PubMed: 23999299 DOI: 10.1107/S0907444913013802 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.18 Å)

Structure validation