45PC

6-conformation model of Escherichia coli dihydrofolate reductase at 100K

Summary for 45PC

• Entry DOI: 10.2210/pdb45pc/pdb
• Descriptor: Dihydrofolate reductase, FOLIC ACID, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... (6 entities in total)
• Functional Keywords: dhfr, folate reductase, tetrahydrofolate regulation, oxidoreductase
• Biological source: Escherichia coli str. K-12 substr. MC4100
• Total number of polymer chains: 1
• Total formula weight: 19381.47

Authors

Passmore, S.K. (deposition date: 2026-09-05, release date: 2026-09-30)

• Primary citation: Passmore, S.K.,Holton, J.M.,Zatsepin, N.A.,Martin, A.V.; Optimizing the connectivity of protein conformations to untangle ensemble refinement; Biorxiv, 2026; DOI: 10.64898/2026.09.17.752399

Experimental method

X-RAY DIFFRACTION (0.85 Å)