3ZWP

Crystal structure of ADP ribosyl cyclase complexed with ara-2'F-ADP- ribose at 2.1 angstrom

Summary for 3ZWP

• Entry DOI: 10.2210/pdb3zwp/pdb
• Related: 1LBE 1R0S 1R12 1R15 1R16 3ZWM 3ZWN 3ZWO
• Descriptor: ADP-RIBOSYL CYCLASE, [(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl [(2R,3R,4R)-4-fluoro-3-hydroxytetrahydrofuran-2-yl]methyl dihydrogen diphosphate, GLYCEROL, ... (4 entities in total)
• Functional Keywords: hydrolase, dp-ribosyl cyclase, cd38, aplysia, binding sites, hydrolysis, nad, protein conformation, substrate specificity
• Biological source: APLYSIA CALIFORNICA (CALIFORNIA SEA HARE)
• Cellular location: Cytoplasmic vesicle: P29241
• Total number of polymer chains: 8
• Total formula weight: 242415.55

Authors

Kotaka, M.,Graeff, R.,Zhang, L.H.,Lee, H.C.,Hao, Q. (deposition date: 2011-08-02, release date: 2011-11-30, Last modification date: 2023-12-20)

• Primary citation: Kotaka, M.,Graeff, R.,Chen, Z.,Zhang, L.H.,Lee, H.C.,Hao, Q.; Structural Studies of Intermediates Along the Cyclization Pathway of Aplysia Adp-Ribosyl Cyclase.; J.Mol.Biol., 415:514-, 2012; PubMed: 22138343; DOI: 10.1016/J.JMB.2011.11.022

Experimental method

X-RAY DIFFRACTION (2.11 Å)