3ZWB

CRYSTAL STRUCTURE OF RAT PEROXISOMAL MULTIFUNCTIONAL ENZYME TYPE 1 (RPMFE1) COMPLEXED WITH 2TRANS-HEXENOYL-COA

3ZWB の概要

• エントリーDOI: 10.2210/pdb3zwb/pdb
• 関連するPDBエントリー: 1ZCJ 2X58 3ZW8 3ZW9 3ZWA 3ZWC
• 分子名称: PEROXISOMAL BIFUNCTIONAL ENZYME, GLYCEROL, (2E)-Hexenoyl-CoA, ... (5 entities in total)
• 機能のキーワード: beta oxidation pathway, oxidoreductase, lipid metabolism, lyase, isomerase, peroxisome, fatty acid metabolism
• 由来する生物種: RATTUS NORVEGICUS (NORWAY RAT)
• 細胞内の位置: Peroxisome: P07896
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 164034.32

構造登録者

Kasaragod, P.,Schmitz, W.,Hiltunen, J.K.,Wierenga, R.K. (登録日: 2011-07-28, 公開日: 2012-08-08, 最終更新日: 2023-12-20)

• 主引用文献: Kasaragod, P.,Schmitz, W.,Kalervo Hiltunen, J.,Wierenga, R.K.; The Isomerase and Hydratase Reaction Mechanism of the Crotonase Active Site of the Multifunctional Enzyme (Type-1), as Deduced from Structures of Complexes with 3S-Hydroxy- Acyl-Coa.; FEBS J., 280:3160-, 2013; PubMed: 23351063; DOI: 10.1111/FEBS.12150

実験手法

X-RAY DIFFRACTION (3.1 Å)