3ZW9

CRYSTAL STRUCTURE OF RAT PEROXISOMAL MULTIFUNCTIONAL ENZYME TYPE 1 (RPMFE1) COMPLEXED WITH (2S,3S)-3-HYDROXY-2-METHYLBUTANOYL-COA

Summary for 3ZW9

Entry DOI	10.2210/pdb3zw9/pdb
Related	1ZCJ 2X58 3ZW8 3ZWA 3ZWB 3ZWC
Descriptor	PEROXISOMAL BIFUNCTIONAL ENZYME, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, (2S,3S)-3-HYDROXY-2-METHYLBUTANOYL-COA, ... (5 entities in total)
Functional Keywords	beta oxidation pathway, oxidoreductase, lipid metabolism, lyase, isomerase, peroxisome, fatty acid metabolism
Biological source	RATTUS NORVEGICUS (NORWAY RAT)
Cellular location	Peroxisome: P07896
Total number of polymer chains	2
Total formula weight	165204.98
Authors	Kasaragod, P.,Schmitz, W.,Hiltunen, J.K.,Wierenga, R.K. (deposition date: 2011-07-28, release date: 2012-08-08, Last modification date: 2013-07-03)
Primary citation	Kasaragod, P.,Schmitz, W.,Kalervo Hiltunen, J.,Wierenga, R.K. The Isomerase and Hydratase Reaction Mechanism of the Crotonase Active Site of the Multifunctional Enzyme (Type-1), as Deduced from Structures of Complexes with 3S-Hydroxy- Acyl-Coa. FEBS J., 280:3160-, 2013 Cited by PubMed: 23351063 DOI: 10.1111/FEBS.12150 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.9 Å)

Structure validation