3ZUS

Crystal structure of an engineered botulinum neurotoxin type A- SNARE23 derivative, LC-A-SNAP23-Hn-A

Summary for 3ZUS

Entry DOI	10.2210/pdb3zus/pdb
Related	1NHL 1UEE 1XTF 1XTG 2VU9 2VUA 2W2D 3BTA 3ZUQ 3ZUR
Descriptor	BOTULINUM NEUROTOXIN TYPE A, SYNAPTOSOMAL-ASSOCIATED PROTEIN 23, ZINC ION (3 entities in total)
Functional Keywords	hydrolase-signaling protein complex, botulinum neurotoxin, snare, protein engineering, hydrolase/signaling protein
Biological source	CLOSTRIDIUM BOTULINUM More
Cellular location	Botulinum neurotoxin A light chain: Secreted. Botulinum neurotoxin A heavy chain: Secreted: P10845
Total number of polymer chains	4
Total formula weight	425461.07
Authors	Masuyer, G.,Stancombe, P.,Chaddock, J.A.,Acharya, K.R. (deposition date: 2011-07-19, release date: 2011-12-07, Last modification date: 2023-12-20)
Primary citation	Masuyer, G.,Stancombe, P.,Chaddock, J.A.,Acharya, K.R. Structures of Engineered Clostridium Botulinum Neurotoxin Derivatives Acta Crystallogr.,Sect.F, 67:1466-, 2011 Cited by PubMed: 22139146 DOI: 10.1107/S1744309111034671 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.95 Å)

Structure validation