3ZUS

Crystal structure of an engineered botulinum neurotoxin type A- SNARE23 derivative, LC-A-SNAP23-Hn-A

3ZUS の概要

• エントリーDOI: 10.2210/pdb3zus/pdb
• 関連するPDBエントリー: 1NHL 1UEE 1XTF 1XTG 2VU9 2VUA 2W2D 3BTA 3ZUQ 3ZUR
• 分子名称: BOTULINUM NEUROTOXIN TYPE A, SYNAPTOSOMAL-ASSOCIATED PROTEIN 23, ZINC ION (3 entities in total)
• 機能のキーワード: hydrolase-signaling protein complex, botulinum neurotoxin, snare, protein engineering, hydrolase/signaling protein
• 由来する生物種: CLOSTRIDIUM BOTULINUM; 詳細
• 細胞内の位置: Botulinum neurotoxin A light chain: Secreted. Botulinum neurotoxin A heavy chain: Secreted: P10845
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 425461.07

構造登録者

Masuyer, G.,Stancombe, P.,Chaddock, J.A.,Acharya, K.R. (登録日: 2011-07-19, 公開日: 2011-12-07, 最終更新日: 2023-12-20)

• 主引用文献: Masuyer, G.,Stancombe, P.,Chaddock, J.A.,Acharya, K.R.; Structures of Engineered Clostridium Botulinum Neurotoxin Derivatives; Acta Crystallogr.,Sect.F, 67:1466-, 2011; PubMed: 22139146; DOI: 10.1107/S1744309111034671

実験手法

X-RAY DIFFRACTION (2.95 Å)