3ZU4

Structure of the enoyl-ACP reductase FabV from Yersinia pestis with the cofactor NADH and the 2-pyridone inhibitor PT172

Summary for 3ZU4

Entry DOI	10.2210/pdb3zu4/pdb
Related	3ZU2 3ZU3 3ZU5
Descriptor	PUTATIVE REDUCTASE YPO4104/Y4119/YP_4011, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, 1-(2-CHLOROBENZYL)-4-HEXYLPYRIDIN-2(1H)-ONE, ... (5 entities in total)
Functional Keywords	oxidoreductase, fatty acid biosynthesis ii, short-chain dehydrogenase reductase superfamily
Biological source	YERSINIA PESTIS
Total number of polymer chains	1
Total formula weight	45024.87
Authors	Hirschbeck, M.W.,Kuper, J.,Tonge, P.J.,Kisker, C. (deposition date: 2011-07-13, release date: 2012-01-18, Last modification date: 2024-05-08)
Primary citation	Hirschbeck, M.W.,Kuper, J.,Lu, H.,Liu, N.,Neckles, C.,Shah, S.,Wagner, S.,Sotriffer, C.A.,Tonge, P.J.,Kisker, C. Structure of the Yersinia Pestis Fabv Enoyl-Acp Reductase and its Interaction with Two 2-Pyridone Inhibitors Structure, 20:89-, 2012 Cited by PubMed: 22244758 DOI: 10.1016/J.STR.2011.07.019 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.01 Å)

Structure validation