3ZU4
Structure of the enoyl-ACP reductase FabV from Yersinia pestis with the cofactor NADH and the 2-pyridone inhibitor PT172
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | PUTATIVE REDUCTASE YPO4104/Y4119/YP_4011 | polymer | 405 | 44032.6 | 1 | UniProt (Q8Z9U1) Pfam (PF12242) Pfam (PF12241) Pfam (PF07055) | YERSINIA PESTIS | ENOYL-ACP REDUCTASE |
| 2 | B (A) | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE | non-polymer | 665.4 | 1 | Chemie (NAI) PubChem (16219774) PubChem (928) PubChem (44119956) PubChem (44415182) PubChem (439153) PubChem (11250888) PubChem (12309341) PubChem (94865921) PubChem (94865923) PubChem (124934832) PubChem (126455899) PubChem (134693949) PubChem (12309339) PubChem (124432988) PubChem (12309347) PubChem (124934831) PubChem (124934833) PubChem (129607000) PubChem (129628338) PubChem (140875346) PubChem (162951601) PubChem (162951600) PubChem (164575491) PubChem (146167236) PubChem (169545638) PubChem (170905224) PubChem (174316169) PubChem (162951602) PubChem (174084875) | |||
| 3 | C (A) | 1-(2-CHLOROBENZYL)-4-HEXYLPYRIDIN-2(1H)-ONE | non-polymer | 303.8 | 1 | Chemie (ZU4) PubChem (54765333) | |||
| 4 | D (A) | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) PubChem (923) | |||
| 5 | E (A) | water | water | 18.0 | 236 | Chemie (HOH) |
Sequence modifications
A: 1 - 399 (UniProt: Q8Z9U1)
| PDB | External Database | Details |
|---|---|---|
| Gly -5 | - | expression tag |
| Ser -4 | - | expression tag |
| His -3 | - | expression tag |
| Met -2 | - | expression tag |
| Leu -1 | - | expression tag |
| Glu 0 | - | expression tag |
| Ser 276 | Thr 276 | variant |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 44032.6 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 992.3 | |
| All* | Total formula weight | 45024.9 |
