3ZTJ

Structure of influenza A neutralizing antibody selected from cultures of single human plasma cells in complex with human H3 Influenza haemagglutinin.

3ZTJ の概要

• エントリーDOI: 10.2210/pdb3ztj/pdb
• 関連するPDBエントリー: 1EO8 1HA0 1HGG 1HTM 1J8H 1QFU 1QU1 2HMG 2VIR 2VIS 2VIT 2VIU 3HMG 3ZTN 4HMG 5HMG
• 分子名称: HEMAGGLUTININ HA1 CHAIN, HEMAGGLUTININ HA2 CHAIN, FI6V3 ANTIBODY HEAVY CHAIN, ... (7 entities in total)
• 機能のキーワード: immune system-viral protein complex, x31, monoclonal antibody, immune system/viral protein
• 由来する生物種: HOMO SAPIENS (HUMAN); 詳細
• 細胞内の位置: Virion membrane ; Single-pass type I membrane protein : P03437 3ZTJ
• タンパク質・核酸の鎖数: 12
• 化学式量合計: 322106.33

構造登録者

Voss, J.E.,Vachieri, S.G.,Gamblin, S.J.,Collins, P.J.,Haire, L.F.,Skehel, J.J. (登録日: 2011-07-08, 公開日: 2011-08-10, 最終更新日: 2020-07-29)

• 主引用文献: Corti, D.,Voss, J.E.,Gamblin, S.J.,Codoni, G.,Macagno, A.,Jarrossay, D.,Vachieri, S.G.,Pinna, D.,Minola, A.,Vanzetta, F.,Silacci, C.,Fernandez-Rodriguez, B.M.,Agatic, G.,Bianchi, S.,Giacchetto-Sasselli, I.,Calder, L.,Sallusto, F.,Collins, P.J.,Haire, L.F.,Temperton, N.,Langedijk, J.P.M.,Skehel, J.J.,Lanzavecchia, A.; A Neutralizing Antibody Selected from Plasma Cells that Binds to Group 1 and Group 2 Influenza a Hemagglutinins.; Science, 333:850-, 2011; PubMed: 21798894; DOI: 10.1126/SCIENCE.1205669

実験手法

X-RAY DIFFRACTION (3.41 Å)