3ZQU
STRUCTURE OF A PROBABLE AROMATIC ACID DECARBOXYLASE
Summary for 3ZQU
| Entry DOI | 10.2210/pdb3zqu/pdb |
| Descriptor | PROBABLE AROMATIC ACID DECARBOXYLASE, 1-DEOXY-1-(7,8-DIMETHYL-2,4-DIOXO-3,4-DIHYDRO-2H-BENZO[G]PTERIDIN-1-ID-10(5H)-YL)-5-O-PHOSPHONATO-D-RIBITOL, SULFATE ION, ... (4 entities in total) |
| Functional Keywords | lyase |
| Biological source | PSEUDOMONAS AERUGINOSA |
| Total number of polymer chains | 1 |
| Total formula weight | 23035.23 |
| Authors | Kopec, J.,Schnell, R.,Schneider, G. (deposition date: 2011-06-11, release date: 2011-11-02, Last modification date: 2023-12-20) |
| Primary citation | Kopec, J.,Schnell, R.,Schneider, G. Structure of Pa4019, a Putative Aromatic Acid Decarboxylase from Pseudomonas Aeruginosa Acta Crystallogr.,Sect.F, 67:1184-, 2011 Cited by PubMed Abstract: The ubiX gene (PA4019) of Pseudomonas aeruginosa has been annotated as encoding a putative 3-octaprenyl-4-hydroxybenzoate decarboxylase from the ubiquinone-biosynthesis pathway. Based on a transposon mutagenesis screen, this gene was also implicated as being essential for the survival of this organism. The crystal structure of recombinant UbiX determined to 1.5 Å resolution showed that the protein belongs to the superfamily of homo-oligomeric flavine-containing cysteine decarboxylases. The enzyme assembles into a dodecamer with 23 point symmetry. The subunit displays a typical Rossmann fold and contains one FMN molecule bound at the interface between two subunits. PubMed: 22102023DOI: 10.1107/S174430911102923X PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.5 Å) |
Structure validation
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