3ZPO

Crystal structure of JmjC domain of human histone demethylase UTY with bound GSK J1

Summary for 3ZPO

• Entry DOI: 10.2210/pdb3zpo/pdb
• Related: 3ZLI
• Descriptor: HISTONE DEMETHYLASE UTY, 3-[[2-pyridin-2-yl-6-(1,2,4,5-tetrahydro-3-benzazepin-3-yl)pyrimidin-4-yl]amino]propanoic acid, ZINC ION, ... (6 entities in total)
• Functional Keywords: hydrolase
• Biological source: HOMO SAPIENS (HUMAN)
• Cellular location: Nucleus : O14607
• Total number of polymer chains: 2
• Total formula weight: 112089.37

Authors

Vollmar, M.,Gileadi, C.,Shrestha, L.,Goubin, S.,Johansson, C.,Krojer, T.,von Delft, F.,Arrowsmith, C.H.,Bountra, C.,Edwards, A.,Oppermann, U. (deposition date: 2013-02-28, release date: 2013-05-29, Last modification date: 2023-12-20)

• Primary citation: Walport, L.J.,Hopkinson, R.J.,Vollmar, M.,Madden, S.K.,Gileadi, C.,Oppermann, U.,Schofield, C.J.,Johansson, C.; Human Uty(Kdm6C) is a Male-Specific Nepislon-Methyl Lysyl Demethylase.; J.Biol.Chem., 289:18302-, 2014; PubMed: 24798337; DOI: 10.1074/JBC.M114.555052

Experimental method

X-RAY DIFFRACTION (2 Å)