3ZKU

Isopenicillin N synthase with substrate analogue AhCV

Summary for 3ZKU

• Entry DOI: 10.2210/pdb3zku/pdb
• Related: 3ZKY
• Descriptor: ISOPENICILLIN N SYNTHASE, FE (III) ION, N-[(5S)-5-amino-5-carboxypentanoyl]-L-homocysteyl-D-valine, ... (4 entities in total)
• Functional Keywords: antibiotic biosynthesis, b-lactam antibiotic, oxidoreductase, oxygenase, penicillin biosynthesis
• Biological source: Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
• Total number of polymer chains: 1
• Total formula weight: 37997.14

Authors

Daruzzaman, A.,Clifton, I.J.,Rutledge, P.J. (deposition date: 2013-01-24, release date: 2013-02-06, Last modification date: 2024-05-08)

• Primary citation: Daruzzaman, A.,Clifton, I.J.,Adlington, R.M.,Baldwin, J.E.,Rutledge, P.J.; The Interaction of Isopenicillin N Synthase with Homologated Substrate Analogues Delta-(L-Alpha-Aminoadipoyl)-L-Homocysteinyl-D-Xaa Characterised by Protein Crystallography.; Chembiochem, 14:599-, 2013; PubMed: 23468426; DOI: 10.1002/CBIC.201200728

Experimental method

X-RAY DIFFRACTION (1.4 Å)