3ZKQ

BACE2 XAPERONE COMPLEX

Summary for 3ZKQ

• Entry DOI: 10.2210/pdb3zkq/pdb
• Related: 3ZKG 3ZKI 3ZKM 3ZKN 3ZKS 3ZKX 3ZL7 3ZOV
• Descriptor: BETA-SECRETASE 2, XA4813, 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... (5 entities in total)
• Functional Keywords: hydrolase-immune system complex, nanobody, hydrolase/immune system
• Biological source: HOMO SAPIENS (HUMAN); More
• Cellular location: Membrane; Single-pass type I membrane protein: Q9Y5Z0
• Total number of polymer chains: 2
• Total formula weight: 55575.70

Authors

Banner, D.W.,Kuglstatter, A.,Benz, J.,Stihle, M.,Ruf, A. (deposition date: 2013-01-24, release date: 2013-05-29, Last modification date: 2023-12-20)

• Primary citation: Banner, D.W.,Gsell, B.,Benz, J.,Bertschinger, J.,Burger, D.,Brack, S.,Cuppuleri, S.,Debulpaep, M.,Gast, A.,Grabulovski, D.,Hennig, M.,Hilpert, H.,Huber, W.,Kuglstatter, A.,Kusznir, E.,Laeremans, T.,Matile, H.,Miscenic, C.,Rufer, A.,Schlatter, D.,Steyeart, J.,Stihle, M.,Thoma, R.,Weber, M.,Ruf, A.; Mapping the Conformational Space Accessible to Bace2 Using Surface Mutants and Co-Crystals with Fab-Fragments, Fynomers, and Xaperones; Acta Crystallogr.,Sect.D, 69:1124-, 2013; PubMed: 23695257; DOI: 10.1107/S0907444913006574

Experimental method

X-RAY DIFFRACTION (1.51 Å)